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Characterization of Brevibacillus laterosporus Cas9 (BlatCas9) for Mammalian Genome Editing

Compact CRISPR/Cas9 systems that can be delivered by AAV for in vivo genome editing hold great promise for clinical applications. Brevibacillus laterosporus Cas9 (BlatCas9) is a compact Cas9 nuclease that has been identified for plant genome editing. Here, we characterize BlatCas9 as an alternative...

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Detalles Bibliográficos
Autores principales:	Gao, Ning, Zhang, Chengdong, Hu, Ziying, Li, Miaomiao, Wei, Jingjing, Wang, Yongming, Liu, Huihui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7604293/ https://www.ncbi.nlm.nih.gov/pubmed/33195228 http://dx.doi.org/10.3389/fcell.2020.583164

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