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Comparison of Anti-oncotic Effect of TRPM4 Blocking Antibody in Neuron, Astrocyte and Vascular Endothelial Cell Under Hypoxia

In stroke and other neurological diseases, Transient Receptor Potential Melastatin 4 (TRPM4) has been reported to cause oncotic cell death which is due to an excessive influx of sodium ions. Following stroke, hypoxia condition activates TRPM4 channel, and the sodium influx via TRPM4 is further enhan...

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Detalles Bibliográficos
Autores principales: Wei, Shunhui, Low, See Wee, Poore, Charlene Priscilla, Chen, Bo, Gao, Yahui, Nilius, Bernd, Liao, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7604339/
https://www.ncbi.nlm.nih.gov/pubmed/33195194
http://dx.doi.org/10.3389/fcell.2020.562584

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