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High Glucose Aggravates Cholesterol Accumulation in Glomerular Endothelial Cells Through the LXRs/LncRNAOR13C9/ABCA1 Regulatory Network

BACKGROUND: The underlying mechanisms by which diabetes and dyslipidemia contribute to diabetic nephropathy (DN) are not fully understood. In this study, we aimed to investigate the role of high glucose (HG) on intracellular cholesterol accumulation in glomerular endothelial cells (GEnCs) and its po...

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Detalles Bibliográficos
Autores principales: Wang, Yao, Xiao, Shumin, Zhou, Saijun, Zhang, Rui, Liu, Hongyan, Lin, Yao, Yu, Pei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7604427/
https://www.ncbi.nlm.nih.gov/pubmed/33192550
http://dx.doi.org/10.3389/fphys.2020.552483

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