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p31(comet) promotes homologous recombination by inactivating REV7 through the TRIP13 ATPase

The repair of DNA double strand breaks (DSBs) that arise from external mutagenic agents and routine cellular processes is essential for life. DSBs are repaired by two major pathways, homologous recombination (HR) and classical nonhomologous end joining (C-NHEJ). DSB repair pathway choice is largely...

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Detalles Bibliográficos
Autores principales: Sarangi, Prabha, Clairmont, Connor S., Galli, Lucas D., Moreau, Lisa A., D’Andrea, Alan D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7604461/
https://www.ncbi.nlm.nih.gov/pubmed/33051298
http://dx.doi.org/10.1073/pnas.2008830117