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IgA as a potential candidate for enteric monoclonal antibody therapeutics with improved gastrointestinal stability
Mucosal surfaces of the gastrointestinal tract play an important role in immune homeostasis and defense and may be compromised by enteric disorders or infection. Therapeutic intervention using monoclonal antibody (mAb) offers the potential for treatment with minimal off-target effects as well as the...
Autores principales: | Wallace, Aaron L., Schneider, Matthew I., Toomey, Jacqueline R., Schneider, Ryan M., Klempner, Mark S., Wang, Yang, Cavacini, Lisa A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7604562/ https://www.ncbi.nlm.nih.gov/pubmed/33041102 http://dx.doi.org/10.1016/j.vaccine.2020.09.070 |
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