SMARCB1 Promotes Ubiquitination and Degradation of NR4A3 via Direct Interaction Driven by ROS in Vascular Endothelial Cell Injury

Nuclear receptor subfamily 4 group A member 3 (NR4A3) protects the vascular endothelial cell (VEC) against hypoxia stress, whose expression is primarily reported to be governed at a transcriptional level. However, the regulation of NR4A3 in the protein level is largely unknown. Here, we report that...

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Detalles Bibliográficos
Autores principales: Lu, Bingzheng, Zhu, Zhu, Sheng, Longxiang, Li, Yuan, Yang, Yang, Chen, Yupin, Xue, Dongdong, Zhou, Yuwei, Cai, Wei, Chen, Chen, Wei, Cailv, Xu, Dong, Yan, Min, Lin, Suizhen, Yan, Guangmei, Yin, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7604603/
https://www.ncbi.nlm.nih.gov/pubmed/33163142
http://dx.doi.org/10.1155/2020/2048210

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