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Leukemia cells remodel marrow adipocytes via TRPV4-dependent lipolysis
Remodeling of adipocyte morphology and function plays a critical role in prostate cancer development. We previously reported that leukemia cells secrete growth differentiation factor 15 (GDF15), which remodels the residual bone marrow (BM) adipocytes into small adipocytes and is associated with a po...
Autores principales: | Yang, Shaoxin, Lu, Wei, Zhao, Chong, Zhai, Yuanmei, Wei, Yanyu, Liu, Jiali, Yu, Yehua, Li, Zhiqiang, Shi, Jun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Fondazione Ferrata Storti
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7604636/ https://www.ncbi.nlm.nih.gov/pubmed/33131246 http://dx.doi.org/10.3324/haematol.2019.225763 |
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