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Leukemia cells remodel marrow adipocytes via TRPV4-dependent lipolysis

Remodeling of adipocyte morphology and function plays a critical role in prostate cancer development. We previously reported that leukemia cells secrete growth differentiation factor 15 (GDF15), which remodels the residual bone marrow (BM) adipocytes into small adipocytes and is associated with a po...

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Detalles Bibliográficos
Autores principales: Yang, Shaoxin, Lu, Wei, Zhao, Chong, Zhai, Yuanmei, Wei, Yanyu, Liu, Jiali, Yu, Yehua, Li, Zhiqiang, Shi, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Fondazione Ferrata Storti 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7604636/
https://www.ncbi.nlm.nih.gov/pubmed/33131246
http://dx.doi.org/10.3324/haematol.2019.225763

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