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Toll-like receptor 2/4 inhibitors can reduce preterm birth in mice

OBJECTIVES: Preterm birth (PTB) occurs in 5% to 18% of newborns. However, the underlying inflammatory mechanisms have not been elucidated. METHODS: We established a mouse model of infection-associated PTB. Physical signs in pregnant mice with or without lipopolysaccharide (LPS) treatment were observ...

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Detalles Bibliográficos
Autores principales: Jing, Xu, Min, Chen, Qi Yun, Liu, Shun Qin, Hu, Li Rui, Li, Jia, Li, Run Mei, Ma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7604950/
https://www.ncbi.nlm.nih.gov/pubmed/33100071
http://dx.doi.org/10.1177/0300060520933795