A Case of Adult-Onset Still's Disease with Positive Antinuclear Antibodies

Adult-onset Still's disease (AOSD) is a rare inflammatory disorder involving multiple systems. It can present a wide range of symptoms like maculopapular rash, fever, and arthralgia, which may overlap with many other disorders, making it difficult to diagnose. Unknown etiology and no diagnostic...

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Autores principales: Lakshman, Harini, Athwal, Pal Satyajit Singh, Gondi, Anitha, Dhillon, Sandaljit, Towfiq, Basim A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2020
Materias:
Internal Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7605080/
https://www.ncbi.nlm.nih.gov/pubmed/33150111
http://dx.doi.org/10.7759/cureus.10761
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author Lakshman, Harini
Athwal, Pal Satyajit Singh
Gondi, Anitha
Dhillon, Sandaljit
Towfiq, Basim A
author_facet Lakshman, Harini
Athwal, Pal Satyajit Singh
Gondi, Anitha
Dhillon, Sandaljit
Towfiq, Basim A
author_sort Lakshman, Harini
collection PubMed
description Adult-onset Still's disease (AOSD) is a rare inflammatory disorder involving multiple systems. It can present a wide range of symptoms like maculopapular rash, fever, and arthralgia, which may overlap with many other disorders, making it difficult to diagnose. Unknown etiology and no diagnostic tests further make it complex to establish the diagnosis of AOSD. We report the case of a 30-year-old female who presented with persistent rash, joint pain, and fever, along with positive antinuclear antibodies (ANA), diagnosed with this condition. The patient improved with corticosteroids and the plan is to start disease-modifying antirheumatic drugs (DMARDs) after tapering off steroids.
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spelling pubmed-76050802020-11-03 A Case of Adult-Onset Still's Disease with Positive Antinuclear Antibodies Lakshman, Harini Athwal, Pal Satyajit Singh Gondi, Anitha Dhillon, Sandaljit Towfiq, Basim A Cureus Internal Medicine Adult-onset Still's disease (AOSD) is a rare inflammatory disorder involving multiple systems. It can present a wide range of symptoms like maculopapular rash, fever, and arthralgia, which may overlap with many other disorders, making it difficult to diagnose. Unknown etiology and no diagnostic tests further make it complex to establish the diagnosis of AOSD. We report the case of a 30-year-old female who presented with persistent rash, joint pain, and fever, along with positive antinuclear antibodies (ANA), diagnosed with this condition. The patient improved with corticosteroids and the plan is to start disease-modifying antirheumatic drugs (DMARDs) after tapering off steroids. Cureus 2020-10-01 /pmc/articles/PMC7605080/ /pubmed/33150111 http://dx.doi.org/10.7759/cureus.10761 Text en Copyright © 2020, Lakshman et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Internal Medicine
Lakshman, Harini
Athwal, Pal Satyajit Singh
Gondi, Anitha
Dhillon, Sandaljit
Towfiq, Basim A
A Case of Adult-Onset Still's Disease with Positive Antinuclear Antibodies
title A Case of Adult-Onset Still's Disease with Positive Antinuclear Antibodies
title_full A Case of Adult-Onset Still's Disease with Positive Antinuclear Antibodies
title_fullStr A Case of Adult-Onset Still's Disease with Positive Antinuclear Antibodies
title_full_unstemmed A Case of Adult-Onset Still's Disease with Positive Antinuclear Antibodies
title_short A Case of Adult-Onset Still's Disease with Positive Antinuclear Antibodies
title_sort case of adult-onset still's disease with positive antinuclear antibodies
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7605080/
https://www.ncbi.nlm.nih.gov/pubmed/33150111
http://dx.doi.org/10.7759/cureus.10761
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