An optogenetic switch for the Set2 methyltransferase provides evidence for transcription-dependent and -independent dynamics of H3K36 methylation

Histone H3 lysine 36 methylation (H3K36me) is a conserved histone modification associated with transcription and DNA repair. Although the effects of H3K36 methylation have been studied, the genome-wide dynamics of H3K36me deposition and removal are not known. We established rapid and reversible opto...

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Detalles Bibliográficos
Autores principales: Lerner, Andrew M., Hepperla, Austin J., Keele, Gregory R., Meriesh, Hashem A., Yumerefendi, Hayretin, Restrepo, David, Zimmerman, Seth, Bear, James E., Kuhlman, Brian, Davis, Ian J., Strahl, Brian D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7605256/
https://www.ncbi.nlm.nih.gov/pubmed/33020206
http://dx.doi.org/10.1101/gr.264283.120

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