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Distinct contributions of DNA methylation and histone acetylation to the genomic occupancy of transcription factors

Epigenetic modifications on chromatin play important roles in regulating gene expression. Although chromatin states are often governed by multilayered structure, how individual pathways contribute to gene expression remains poorly understood. For example, DNA methylation is known to regulate transcr...

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Detalles Bibliográficos
Autores principales: Cusack, Martin, King, Hamish W., Spingardi, Paolo, Kessler, Benedikt M., Klose, Robert J., Kriaucionis, Skirmantas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7605266/
https://www.ncbi.nlm.nih.gov/pubmed/32963030
http://dx.doi.org/10.1101/gr.257576.119