The Greatwall kinase safeguards the genome integrity by affecting the kinome activity in mitosis

Progression through mitosis is balanced by the timely regulation of phosphorylation and dephosphorylation events ensuring the correct segregation of chromosomes before cytokinesis. This balance is regulated by the opposing actions of CDK1 and PP2A, as well as the Greatwall kinase/MASTL. MASTL is com...

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Detalles Bibliográficos
Autores principales: Bisteau, Xavier, Lee, Joann, Srinivas, Vinayaka, Lee, Joanna H. S., Niska-Blakie, Joanna, Tan, Gifford, Yap, Shannon Y. X., Hom, Kevin W., Wong, Cheng Kit, Chae, Jeongjun, Wang, Loo Chien, Kim, Jinho, Rancati, Giulia, Sobota, Radoslaw M., Tan, Chris S. H., Kaldis, Philipp
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7605441/
https://www.ncbi.nlm.nih.gov/pubmed/32978522
http://dx.doi.org/10.1038/s41388-020-01470-1

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