Dysregulation of tryptophan catabolism at the host-skin microbiota interface in hidradenitis suppurativa

Hidradenitis suppurativa (HS) is a chronic skin disorder of unknown etiology that manifests as recurrent, painful lesions. Cutaneous dysbiosis and unresolved inflammation are hallmarks of active HS, but their origin and interplay remain unclear. Our metabolomic profiling of HS skin revealed an abnor...

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Detalles Bibliográficos
Autores principales: Guenin-Macé, Laure, Morel, Jean-David, Doisne, Jean-Marc, Schiavo, Angèle, Boulet, Lysiane, Mayau, Véronique, Goncalves, Pedro, Duchatelet, Sabine, Hovnanian, Alain, Bondet, Vincent, Duffy, Darragh, Ungeheuer, Marie-Noëlle, Delage, Maïa, Nassif, Aude, Di Santo, James P., Demangel, Caroline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7605522/
https://www.ncbi.nlm.nih.gov/pubmed/32970636
http://dx.doi.org/10.1172/jci.insight.140598

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