TRPV4 channels are essential for alveolar epithelial barrier function as protection from lung edema

Ischemia/reperfusion-induced edema (IRE), one of the most significant causes of mortality after lung transplantation, can be mimicked ex vivo in isolated perfused mouse lungs (IPL). Transient receptor potential vanilloid 4 (TRPV4) is a nonselective cation channel studied in endothelium; however, its...

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Detalles Bibliográficos
Autores principales: Weber, Jonas, Rajan, Suhasini, Schremmer, Christian, Chao, Yu-Kai, Krasteva-Christ, Gabriela, Kannler, Martina, Yildirim, Ali Önder, Brosien, Monika, Schredelseker, Johann, Weissmann, Norbert, Grimm, Christian, Gudermann, Thomas, Dietrich, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7605532/
https://www.ncbi.nlm.nih.gov/pubmed/32931478
http://dx.doi.org/10.1172/jci.insight.134464

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