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Exercise intolerance and rapid skeletal muscle energetic decline in human age-associated frailty

BACKGROUND: Physical frailty in older individuals is characterized by subjective symptoms of fatigue and exercise intolerance (EI). Objective abnormalities in skeletal muscle (SM) mitochondrial high-energy phosphate (HEP) metabolism contribute to EI in inherited myopathies; however, their presence o...

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Detalles Bibliográficos
Autores principales:	Lewsey, Sabra C., Weiss, Kilian, Schär, Michael, Zhang, Yi, Bottomley, Paul A., Samuel, T. Jake, Xue, Qian-Li, Steinberg, Angela, Walston, Jeremy D., Gerstenblith, Gary, Weiss, Robert G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Clinical Investigation 2020
Materias:	Clinical Medicine
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7605538/ https://www.ncbi.nlm.nih.gov/pubmed/32941181 http://dx.doi.org/10.1172/jci.insight.141246

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