Type I Interferon Transcriptional Network Regulates Expression of Coinhibitory Receptors in Human T cells

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While inhibition of T cell co-inhibitory receptors has revolutionized cancer therapy, the mechanisms governing their expression on human T cells have not been elucidated. Type 1 interferon (IFN-I) modulates T cell immunity in viral infection, autoimmunity, and cancer, and may facilitate induction of...

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Detalles Bibliográficos
Autores principales: Sumida, Tomokazu S., Dulberg, Shai, Schupp, Jonas, Stillwell, Helen A., Axisa, Pierre-Paul, Comi, Michela, Lincoln, Matthew, Unterman, Avraham, Kaminski, Naftali, Madi, Asaf, Kuchroo, Vijay K., Hafler, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7605554/
https://www.ncbi.nlm.nih.gov/pubmed/33140047
http://dx.doi.org/10.1101/2020.10.30.362947
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