Synergism of TNF-α and IFN-γ triggers inflammatory cell death, tissue damage, and mortality in SARS-CoV-2 infection and cytokine shock syndromes

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The COVID-19 pandemic has caused significant morbidity and mortality. Currently, there is a critical shortage of proven treatment options and an urgent need to understand the pathogenesis of multi-organ failure and lung damage. Cytokine storm is associated with severe inflammation and organ damage d...

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Detalles Bibliográficos
Autores principales: Karki, Rajendra, Sharma, Bhesh Raj, Tuladhar, Shraddha, Williams, Evan Peter, Zalduondo, Lillian, Samir, Parimal, Zheng, Min, Sundaram, Balamurugan, Banoth, Balaji, Malireddi, R. K. Subbarao, Schreiner, Patrick, Neale, Geoffrey, Vogel, Peter, Webby, Richard, Jonsson, Colleen Beth, Kanneganti, Thirumala-Devi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7605562/
https://www.ncbi.nlm.nih.gov/pubmed/33140051
http://dx.doi.org/10.1101/2020.10.29.361048

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