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Interferon Regulatory Factor-1 (IRF1) activates autophagy to promote liver ischemia/reperfusion injury by inhibiting β-catenin in mice
Autophagy is an important factor in liver ischemia-reperfusion injury. In the current study we investigate the function of interferon regulatory factor-1 (IRF1) in regulating autophagy to promote hepatic ischemia reperfusion injury (IR). The high expression of IRF1 during hepatic IR exhibited increa...
Autores principales: | Yan, Bing, Luo, Jing, Kaltenmeier, Christof, Du, Qiang, Stolz, Donna B., Loughran, Patricia, Yan, Yihe, Cui, Xiao, Geller, David A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7605671/ https://www.ncbi.nlm.nih.gov/pubmed/33137133 http://dx.doi.org/10.1371/journal.pone.0239119 |
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