Cargando…
Drosophila phosphatidylinositol-4 kinase fwd promotes mitochondrial fission and can suppress Pink1/parkin phenotypes
Balanced mitochondrial fission and fusion play an important role in shaping and distributing mitochondria, as well as contributing to mitochondrial homeostasis and adaptation to stress. In particular, mitochondrial fission is required to facilitate degradation of damaged or dysfunctional units via m...
Autores principales: | Terriente-Felix, Ana, Wilson, Emma L., Whitworth, Alexander J. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7605714/ https://www.ncbi.nlm.nih.gov/pubmed/33085661 http://dx.doi.org/10.1371/journal.pgen.1008844 |
Ejemplares similares
-
Atg1-mediated autophagy suppresses tissue degeneration in pink1/parkin mutants by promoting mitochondrial fission in Drosophila
por: Ma, Peng, et al.
Publicado: (2018) -
The STING pathway does not contribute to behavioural or mitochondrial phenotypes in Drosophila Pink1/parkin or mtDNA mutator models
por: Lee, Juliette J., et al.
Publicado: (2020) -
Superoxide dismutating molecules rescue the toxic effects of PINK1 and parkin loss
por: Biosa, Alice, et al.
Publicado: (2018) -
PINK1-Mediated Phosphorylation of Parkin Boosts Parkin Activity in Drosophila
por: Shiba-Fukushima, Kahori, et al.
Publicado: (2014) -
Basal mitophagy is widespread in Drosophila but minimally affected by loss of Pink1 or parkin
por: Lee, Juliette J., et al.
Publicado: (2018)