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Intra-host non-synonymous diversity at a neutralizing antibody epitope of SARS-CoV-2 spike protein N-terminal domain

OBJECTIVES: SARS-CoV-2 has evolved rapidly into several genetic clusters. However, data on mutations during the course of infection are scarce. This study aims to determine viral genome diversity in serial samples of COVID-19 patients. METHODS: Targeted deep sequencing of the spike gene was performe...

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Detalles Bibliográficos
Autores principales:	Ip, Jonathan Daniel, Kok, Kin-Hang, Chan, Wan-Mui, Chu, Allen Wing-Ho, Wu, Wai-Lan, Yip, Cyril Chik-Yan, To, Wing-Kin, Tsang, Owen Tak-Yin, Leung, Wai-Shing, Chik, Thomas Shiu-Hong, Chan, Kwok-Hung, Hung, Ivan Fan-Ngai, Yuen, Kwok-Yung, To, Kelvin Kai-Wang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	European Society of Clinical Microbiology and Infectious Diseases. Published by Elsevier Ltd. 2021
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7605743/ https://www.ncbi.nlm.nih.gov/pubmed/33144203 http://dx.doi.org/10.1016/j.cmi.2020.10.030

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