Intracranial Hemorrhage in Hospitalized SARS-CoV-2 Patients: A Case Series

The SARS-CoV-2 virus causing Coronavirus Disease 2019 (COVID-19) is a global pandemic with almost 30 million confirmed worldwide cases. Prothrombotic complications arising from those affected with severe symptoms have been reported in various medical journals. Currently, clinical trials are underway...

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Autores principales: Mousa-Ibrahim, Fady, Berg, Stephanie, Od`TPDetola, Oluwatobi, Teitcher, Michael, Ruland, Sean
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7605803/
https://www.ncbi.nlm.nih.gov/pubmed/33161349
http://dx.doi.org/10.1016/j.jstrokecerebrovasdis.2020.105428
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author Mousa-Ibrahim, Fady
Berg, Stephanie
Od`TPDetola, Oluwatobi
Teitcher, Michael
Ruland, Sean
author_facet Mousa-Ibrahim, Fady
Berg, Stephanie
Od`TPDetola, Oluwatobi
Teitcher, Michael
Ruland, Sean
author_sort Mousa-Ibrahim, Fady
collection PubMed
description The SARS-CoV-2 virus causing Coronavirus Disease 2019 (COVID-19) is a global pandemic with almost 30 million confirmed worldwide cases. Prothrombotic complications arising from those affected with severe symptoms have been reported in various medical journals. Currently, clinical trials are underway to address the questions regarding anticoagulation dosing strategies to prevent thrombosis for these critically ill patients. However, given the increasing use of therapeutic anticoagulation in patients admitted with COVID-19 to curtail this prothrombotic state, our institution has witnessed six cases of devastating intracranial hemorrhage as well as thrombosis leading to five fatalities and we examine their hospital course and anticoagulation used.
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spelling pubmed-76058032020-11-03 Intracranial Hemorrhage in Hospitalized SARS-CoV-2 Patients: A Case Series Mousa-Ibrahim, Fady Berg, Stephanie Od`TPDetola, Oluwatobi Teitcher, Michael Ruland, Sean J Stroke Cerebrovasc Dis Article The SARS-CoV-2 virus causing Coronavirus Disease 2019 (COVID-19) is a global pandemic with almost 30 million confirmed worldwide cases. Prothrombotic complications arising from those affected with severe symptoms have been reported in various medical journals. Currently, clinical trials are underway to address the questions regarding anticoagulation dosing strategies to prevent thrombosis for these critically ill patients. However, given the increasing use of therapeutic anticoagulation in patients admitted with COVID-19 to curtail this prothrombotic state, our institution has witnessed six cases of devastating intracranial hemorrhage as well as thrombosis leading to five fatalities and we examine their hospital course and anticoagulation used. Elsevier Inc. 2021-01 2020-11-02 /pmc/articles/PMC7605803/ /pubmed/33161349 http://dx.doi.org/10.1016/j.jstrokecerebrovasdis.2020.105428 Text en © 2020 Elsevier Inc. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Mousa-Ibrahim, Fady
Berg, Stephanie
Od`TPDetola, Oluwatobi
Teitcher, Michael
Ruland, Sean
Intracranial Hemorrhage in Hospitalized SARS-CoV-2 Patients: A Case Series
title Intracranial Hemorrhage in Hospitalized SARS-CoV-2 Patients: A Case Series
title_full Intracranial Hemorrhage in Hospitalized SARS-CoV-2 Patients: A Case Series
title_fullStr Intracranial Hemorrhage in Hospitalized SARS-CoV-2 Patients: A Case Series
title_full_unstemmed Intracranial Hemorrhage in Hospitalized SARS-CoV-2 Patients: A Case Series
title_short Intracranial Hemorrhage in Hospitalized SARS-CoV-2 Patients: A Case Series
title_sort intracranial hemorrhage in hospitalized sars-cov-2 patients: a case series
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7605803/
https://www.ncbi.nlm.nih.gov/pubmed/33161349
http://dx.doi.org/10.1016/j.jstrokecerebrovasdis.2020.105428
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