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Interacting with α7 nAChR is a new mechanism for AChE to enhance the inflammatory response in macrophages

Acetylcholine (ACh) regulates inflammation via α7 nicotinic acetylcholine receptor (α7 nAChR). Acetylcholinesterase (AChE), an enzyme hydrolyzing ACh, is expressed in immune cells suggesting non-classical function in inflammatory responses. Here, the expression of PRiMA-linked G4 AChE was identified...

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Detalles Bibliográficos
Autores principales: Liu, Etta Y.L., Xia, Yingjie, Kong, Xiangpeng, Guo, Maggie S.S., Yu, Anna X.D., Zheng, Brody Z.Y., Mak, Shinghung, Xu, Miranda L., Tsim, Karl W.K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7606108/
https://www.ncbi.nlm.nih.gov/pubmed/33163344
http://dx.doi.org/10.1016/j.apsb.2020.05.005