Cargando…

Nature-derived compounds modulating Wnt/β-catenin pathway: a preventive and therapeutic opportunity in neoplastic diseases

The Wnt/β-catenin signaling is a conserved pathway that has a crucial role in embryonic and adult life. Dysregulation of the Wnt/β-catenin pathway has been associated with diseases including cancer, and components of the signaling have been proposed as innovative therapeutic targets, mainly for canc...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sferrazza, Gianluca, Corti, Marco, Brusotti, Gloria, Pierimarchi, Pasquale, Temporini, Caterina, Serafino, Annalucia, Calleri, Enrica
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2020
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7606110/ https://www.ncbi.nlm.nih.gov/pubmed/33163337 http://dx.doi.org/10.1016/j.apsb.2019.12.019

Ejemplares similares

Hovenia dulcis Thumberg: Phytochemistry, Pharmacology, Toxicology and Regulatory Framework for Its Use in the European Union
por: Sferrazza, Gianluca, et al.
Publicado: (2021)

Bioassay-Guided Isolation of Nigracin, Responsible for the Tissue Repair Properties of Drypetes Klainei Stem Bark
por: Sferrazza, Gianluca, et al.
Publicado: (2020)

The Iterative Development of Medicines Through the European Medicine Agency's Adaptive Pathway Approach
por: Nicotera, Giuseppe, et al.
Publicado: (2019)

Atrial Natriuretic Peptide Acts as a Neuroprotective Agent in in Vitro Models of Parkinson’s Disease via Up-regulation of the Wnt/β-Catenin Pathway
por: Colini Baldeschi, Arianna, et al.
Publicado: (2018)

Essential Oil from Eucalyptus globulus (Labill.) Activates Complement Receptor-Mediated Phagocytosis and Stimulates Podosome Formation in Human Monocyte-Derived Macrophages
por: Zonfrillo, Manuela, et al.
Publicado: (2022)

Monolithic Papain-Immobilized Enzyme Reactors for Automated Structural Characterization of Monoclonal Antibodies
por: Rinaldi, Francesca, et al.
Publicado: (2021)

The Wnt/β-catenin signaling: a multifunctional target for neuroprotective and regenerative strategies in Parkinson’s disease
por: Serafino, Annalucia, et al.
Publicado: (2022)

WNT-pathway components as predictive markers useful for diagnosis, prevention and therapy in inflammatory bowel disease and sporadic colorectal cancer
por: Serafino, Annalucia, et al.
Publicado: (2014)

Bio-Guided Fractionation of Stem Bark Extracts from Phyllanthus muellarianus: Identification of Phytocomponents with Anti-Cholinesterase Activity
por: Naldi, Marina, et al.
Publicado: (2021)

Editorial: Analytical devices based on immobilized macromolecules for structural and activity/affinity studies in drug discovery
por: Temporini, Caterina, et al.
Publicado: (2022)

Atrial Natriuretic Peptide: A Magic Bullet for Cancer Therapy Targeting Wnt Signaling and Cellular pH Regulators
por: Serafino, A., et al.
Publicado: (2014)

Stimulatory effect of Eucalyptus essential oil on innate cell-mediated immune response
por: Serafino, Annalucia, et al.
Publicado: (2008)

Activation of human endogenous retrovirus K (HERV-K) and cellular modifications in human melanoma cell line: transcriptional profiling analysis
por: Balestrieri, Emanuela, et al.
Publicado: (2009)

Natriuretic peptides are neuroprotective on in vitro models of PD and promote dopaminergic differentiation of hiPSCs-derived neurons via the Wnt/β-catenin signaling
por: Giovannini, Daniela, et al.
Publicado: (2021)

IRS1 Regulation by Wnt/β-Catenin Signaling and Varied Contribution of IRS1 to the Neoplastic Phenotype
por: Bommer, Guido T., et al.
Publicado: (2010)

Glycovaccine Design: Optimization of Model and Antitubercular Carrier Glycosylation via Disuccinimidyl Homobifunctional Linker
por: Tengattini, Sara, et al.
Publicado: (2023)

Betulinic acid is a PPARγ antagonist that improves glucose uptake, promotes osteogenesis and inhibits adipogenesis
por: Brusotti, Gloria, et al.
Publicado: (2017)

Wnt/β-catenin signalling: function, biological mechanisms, and therapeutic opportunities
por: Liu, Jiaqi, et al.
Publicado: (2022)

WNT/β-Catenin Pathway in Soft Tissue Sarcomas: New Therapeutic Opportunities?
por: Martinez-Font, Esther, et al.
Publicado: (2021)

Activation Status of Wnt/ß-Catenin Signaling in Normal and Neoplastic Breast Tissues: Relationship to HER2/neu Expression in Human and Mouse
por: Khalil, Sara, et al.
Publicado: (2012)

The natural compound Jatrophone interferes with Wnt/β-catenin signaling and inhibits proliferation and EMT in human triple-negative breast cancer
por: Fatima, Iram, et al.
Publicado: (2017)

Multifaceted roles of GSK-3 and Wnt/β-catenin in hematopoiesis and leukemogenesis: opportunities for therapeutic intervention
por: McCubrey, J A, et al.
Publicado: (2014)

Activation of Wnt/β-catenin signaling in abdominal aortic aneurysm: A potential therapeutic opportunity?
por: Puertas-Umbert, Lídia, et al.
Publicado: (2022)

WNT/β-catenin signaling in hepatocellular carcinoma: The aberrant activation, pathogenic roles, and therapeutic opportunities
por: Gajos-Michniewicz, Anna, et al.
Publicado: (2023)

Correction: The natural compound Jatrophone interferes with Wnt/β-catenin signaling and inhibits proliferation and EMT in human triple-negative breast cancer
por: Fatima, Iram, et al.
Publicado: (2018)

Jasmonate Compounds and Their Derivatives in the Regulation of the Neoplastic Processes
por: Jarocka-Karpowicz, Iwona, et al.
Publicado: (2021)

Extracellular Vesicles: Novel Opportunities to Understand and Detect Neoplastic Diseases
por: Bongiovanni, Laura, et al.
Publicado: (2021)

From advanced diagnosis to advanced resection in early neoplastic colorectal lesions: Never-ending and trending topics in the 2020s
por: Auriemma, Francesco, et al.
Publicado: (2022)

Hydrostatic Pressure Regulates MicroRNA Expression Levels in Osteoarthritic Chondrocyte Cultures via the Wnt/β-Catenin Pathway
por: Cheleschi, Sara, et al.
Publicado: (2017)

WNKs in Wnt/β-catenin signaling
por: Serysheva, Ekatherina, et al.
Publicado: (2014)

Wnt/β-Catenin Signaling and Obesity
por: Chen, Na, et al.
Publicado: (2018)

Wnt2 complements Wnt/β-catenin signaling in colorectal cancer
por: Jung, Youn-Sang, et al.
Publicado: (2015)

Surrogate Wnt agonists that phenocopy canonical Wnt/β-catenin signaling
por: Janda, Claudia Y., et al.
Publicado: (2017)

Running Against the Wnt: How Wnt/β-Catenin Suppresses Adipogenesis
por: de Winter, Twan J. J., et al.
Publicado: (2021)

Inhibition of Melanogenesis by the Pyridinyl Imidazole Class of Compounds: Possible Involvement of the Wnt/β-Catenin Signaling Pathway
por: Bellei, Barbara, et al.
Publicado: (2012)

Preferential Inhibition of Wnt/β-Catenin Signaling by Novel Benzimidazole Compounds in Triple-Negative Breast Cancer
por: Gangrade, Abhishek, et al.
Publicado: (2018)

Identification of quinazoline compounds as novel potent inhibitors of Wnt/β-catenin signaling in colorectal cancer cells
por: Li, Yonghe, et al.
Publicado: (2016)

A Re-evaluation of the “Oncogenic” Nature of Wnt/β-catenin Signaling in Melanoma and Other Cancers
por: Lucero, Olivia M., et al.
Publicado: (2010)

Natural Killer Cells: Diverse Functions in Tumor Immunity and Defects in Pre-neoplastic and Neoplastic Stages of Tumorigenesis
por: Jewett, Anahid, et al.
Publicado: (2019)

Surface Plasmon Resonance as a Tool for Ligand Binding Investigation of Engineered GPR17 Receptor, a G Protein Coupled Receptor Involved in Myelination
por: Capelli, Davide, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_ssfqqdbmrsrshcfkhq2sg4q12k