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Early-onset neonatal sepsis: Organism patterns between 2009 and 2014
OBJECTIVE: To evaluate trends in organisms causing early-onset neonatal sepsis (EONS). Congruent with recent reports, we hypothesized there would be an increase in EONS caused by Escherichia coli. STUDY DESIGN: National data on infants admitted to neonatal intensive care units from 2009 to 2014 were...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7606168/ https://www.ncbi.nlm.nih.gov/pubmed/33173553 http://dx.doi.org/10.1093/pch/pxz073 |
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author | Sgro, Michael Campbell, Douglas M Mellor, Kaitlyn L Hollamby, Kathleen Bodani, Jaya Shah, Prakesh S |
author_facet | Sgro, Michael Campbell, Douglas M Mellor, Kaitlyn L Hollamby, Kathleen Bodani, Jaya Shah, Prakesh S |
author_sort | Sgro, Michael |
collection | PubMed |
description | OBJECTIVE: To evaluate trends in organisms causing early-onset neonatal sepsis (EONS). Congruent with recent reports, we hypothesized there would be an increase in EONS caused by Escherichia coli. STUDY DESIGN: National data on infants admitted to neonatal intensive care units from 2009 to 2014 were compared to previously reported data from 2003 to 2008. We report 430 cases of EONS from 2009 to 2014. Bivariate analyses were used to analyze the distribution of causative organisms over time and differences by gestational age. Linear regression was used to estimate trends in causative organisms. RESULTS: Since 2003, there has been a trend of increasing numbers of cases caused by E coli (P<0.01). The predominant organism was E coli in preterm infants and Group B Streptococcus in term infants. CONCLUSIONS: With the majority of EONS cases now caused by E coli, our findings emphasize the importance of continued surveillance of causative organism patterns and developing approaches to reduce cases caused by E coli. |
format | Online Article Text |
id | pubmed-7606168 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-76061682020-11-09 Early-onset neonatal sepsis: Organism patterns between 2009 and 2014 Sgro, Michael Campbell, Douglas M Mellor, Kaitlyn L Hollamby, Kathleen Bodani, Jaya Shah, Prakesh S Paediatr Child Health Original Articles OBJECTIVE: To evaluate trends in organisms causing early-onset neonatal sepsis (EONS). Congruent with recent reports, we hypothesized there would be an increase in EONS caused by Escherichia coli. STUDY DESIGN: National data on infants admitted to neonatal intensive care units from 2009 to 2014 were compared to previously reported data from 2003 to 2008. We report 430 cases of EONS from 2009 to 2014. Bivariate analyses were used to analyze the distribution of causative organisms over time and differences by gestational age. Linear regression was used to estimate trends in causative organisms. RESULTS: Since 2003, there has been a trend of increasing numbers of cases caused by E coli (P<0.01). The predominant organism was E coli in preterm infants and Group B Streptococcus in term infants. CONCLUSIONS: With the majority of EONS cases now caused by E coli, our findings emphasize the importance of continued surveillance of causative organism patterns and developing approaches to reduce cases caused by E coli. Oxford University Press 2019-08-09 /pmc/articles/PMC7606168/ /pubmed/33173553 http://dx.doi.org/10.1093/pch/pxz073 Text en © The Author(s) 2019. Published by Oxford University Press on behalf of the Canadian Paediatric Society. http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Articles Sgro, Michael Campbell, Douglas M Mellor, Kaitlyn L Hollamby, Kathleen Bodani, Jaya Shah, Prakesh S Early-onset neonatal sepsis: Organism patterns between 2009 and 2014 |
title | Early-onset neonatal sepsis: Organism patterns between 2009 and 2014 |
title_full | Early-onset neonatal sepsis: Organism patterns between 2009 and 2014 |
title_fullStr | Early-onset neonatal sepsis: Organism patterns between 2009 and 2014 |
title_full_unstemmed | Early-onset neonatal sepsis: Organism patterns between 2009 and 2014 |
title_short | Early-onset neonatal sepsis: Organism patterns between 2009 and 2014 |
title_sort | early-onset neonatal sepsis: organism patterns between 2009 and 2014 |
topic | Original Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7606168/ https://www.ncbi.nlm.nih.gov/pubmed/33173553 http://dx.doi.org/10.1093/pch/pxz073 |
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