Serine restriction alters sphingolipid diversity to constrain tumor growth

Serine, glycine, and other non-essential amino acids are critical for tumor progression, and strategies to limit their availability are emerging as potential cancer therapies(1–3). However, the molecular mechanisms driving this response remain unclear, and the impact on lipid metabolism is relativel...

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Detalles Bibliográficos
Autores principales: Muthusamy, Thangaselvam, Cordes, Thekla, Handzlik, Michal K., You, Le, Lim, Esther W., Gengatharan, Jivani, Pinto, Antonio F. M., Badur, Mehmet G., Kolar, Matthew J., Wallace, Martina, Saghatelian, Alan, Metallo, Christian M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7606299/
https://www.ncbi.nlm.nih.gov/pubmed/32788725
http://dx.doi.org/10.1038/s41586-020-2609-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7606299/
https://www.ncbi.nlm.nih.gov/pubmed/32788725
http://dx.doi.org/10.1038/s41586-020-2609-x

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