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Serine restriction alters sphingolipid diversity to constrain tumor growth
Serine, glycine, and other non-essential amino acids are critical for tumor progression, and strategies to limit their availability are emerging as potential cancer therapies(1–3). However, the molecular mechanisms driving this response remain unclear, and the impact on lipid metabolism is relativel...
| Autores principales: | , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7606299/ https://www.ncbi.nlm.nih.gov/pubmed/32788725 http://dx.doi.org/10.1038/s41586-020-2609-x |