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Effects of capillary refill time-vs. lactate-targeted fluid resuscitation on regional, microcirculatory and hypoxia-related perfusion parameters in septic shock: a randomized controlled trial
BACKGROUND: Persistent hyperlactatemia has been considered as a signal of tissue hypoperfusion in septic shock patients, but multiple non-hypoperfusion-related pathogenic mechanisms could be involved. Therefore, pursuing lactate normalization may lead to the risk of fluid overload. Peripheral perfus...
Autores principales: | Castro, Ricardo, Kattan, Eduardo, Ferri, Giorgio, Pairumani, Ronald, Valenzuela, Emilio Daniel, Alegría, Leyla, Oviedo, Vanessa, Pavez, Nicolás, Soto, Dagoberto, Vera, Magdalena, Santis, César, Astudillo, Brusela, Cid, María Alicia, Bravo, Sebastian, Ospina-Tascón, Gustavo, Bakker, Jan, Hernández, Glenn |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7606372/ https://www.ncbi.nlm.nih.gov/pubmed/33140173 http://dx.doi.org/10.1186/s13613-020-00767-4 |
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