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Developing a pathway-independent and full-autonomous global resource allocation strategy to dynamically switching phenotypic states
A grand challenge of biological chemical production is the competition between synthetic circuits and host genes for limited cellular resources. Quorum sensing (QS)-based dynamic pathway regulations provide a pathway-independent way to rebalance metabolic flux over the course of the fermentation. Mo...
Autores principales: | Wu, Junjun, Bao, Meijiao, Duan, Xuguo, Zhou, Peng, Chen, Caiwen, Gao, Jiahua, Cheng, Shiyao, Zhuang, Qianqian, Zhao, Zhijun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7606477/ https://www.ncbi.nlm.nih.gov/pubmed/33139748 http://dx.doi.org/10.1038/s41467-020-19432-2 |
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