Proteasome Composition and Activity Changes in Cultured Fibroblasts Derived From Mucopolysaccharidoses Patients and Their Modulation by Genistein

In this study, we have asked whether proteasome composition and function are affected in cells derived from patients suffering from all types of mucopolysaccharidosis (MPS), an inherited metabolic disease caused by accumulation of undegraded glycosaminoglycans (GAGs). Moreover, we have tested if gen...

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Detalles Bibliográficos
Autores principales: Pierzynowska, Karolina, Gaffke, Lidia, Jankowska, Elżbieta, Rintz, Estera, Witkowska, Julia, Wieczerzak, Ewa, Podlacha, Magdalena, Węgrzyn, Grzegorz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7606483/
https://www.ncbi.nlm.nih.gov/pubmed/33195185
http://dx.doi.org/10.3389/fcell.2020.540726

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7606483/
https://www.ncbi.nlm.nih.gov/pubmed/33195185
http://dx.doi.org/10.3389/fcell.2020.540726

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