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Construction of a complete set of Neisseria meningitidis mutants and its use for the phenotypic profiling of this human pathogen

The bacterium Neisseria meningitidis causes life-threatening meningitis and sepsis. Here, we construct a complete collection of defined mutants in protein-coding genes of this organism, identifying all genes that are essential under laboratory conditions. The collection, named NeMeSys 2.0, consists...

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Detalles Bibliográficos
Autores principales: Muir, Alastair, Gurung, Ishwori, Cehovin, Ana, Bazin, Adelme, Vallenet, David, Pelicic, Vladimir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7606547/
https://www.ncbi.nlm.nih.gov/pubmed/33139723
http://dx.doi.org/10.1038/s41467-020-19347-y