Extensive 5′-surveillance guards against non-canonical NAD-caps of nuclear mRNAs in yeast

The ubiquitous redox coenzyme nicotinamide adenine dinucleotide (NAD) acts as a non-canonical cap structure on prokaryotic and eukaryotic ribonucleic acids. Here we find that in budding yeast, NAD-RNAs are abundant (>1400 species), short (<170 nt), and mostly correspond to mRNA 5′-ends. The mo...

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Detalles Bibliográficos
Autores principales: Zhang, Yaqing, Kuster, David, Schmidt, Tobias, Kirrmaier, Daniel, Nübel, Gabriele, Ibberson, David, Benes, Vladimir, Hombauer, Hans, Knop, Michael, Jäschke, Andres
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7606564/
https://www.ncbi.nlm.nih.gov/pubmed/33139726
http://dx.doi.org/10.1038/s41467-020-19326-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7606564/
https://www.ncbi.nlm.nih.gov/pubmed/33139726
http://dx.doi.org/10.1038/s41467-020-19326-3

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