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Noninvasive Detection of Active Microcalcification in an Occlusive Peripheral Vascular Aneurysm Using (18)F-NaF PET/CT Imaging

A 65-year-old man with an occluded popliteal artery aneurysm and calf claudication underwent PET/CT imaging with (18)F-NaF to assess the status of active microcalcification in the aneurysm site and additional lower extremity arteries. CT imaging revealed macrocalcification of the aneurysm that coloc...

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Detalles Bibliográficos
Autores principales: Eisert, Susan Natalie, Chou, Ting-Heng, Bobbey, Adam J., Go, Michael R., Stacy, Mitchel R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7606725/
https://www.ncbi.nlm.nih.gov/pubmed/33086277
http://dx.doi.org/10.1097/RLU.0000000000003344
Descripción
Sumario:A 65-year-old man with an occluded popliteal artery aneurysm and calf claudication underwent PET/CT imaging with (18)F-NaF to assess the status of active microcalcification in the aneurysm site and additional lower extremity arteries. CT imaging revealed macrocalcification of the aneurysm that colocalized with elevated retention of (18)F-NaF on PET images. PET/CT detected additional distal arterial sites with focal uptake of (18)F-NaF that did not coincide with CT-detectable macrocalcification. This report highlights a case of active microcalcification in an occlusive peripheral aneurysm using PET/CT. PET/CT may provide molecular insight into the remodeling of lower extremity aneurysms and atherosclerotic lesions.