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The Ras-ERK signaling pathway regulates acetylated activating transcription factor 2 via p300 in pancreatic cancer cells

BACKGROUND: Activating transcription factor 2 (ATF2) regulates the expression of downstream target genes and is phosphorylated by the Ras-extracellular-signal-regulated kinase (ERK) pathway. Acetylation of ATF2 is necessary for this type of regulation. However, the molecular mechanism by which the R...

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Detalles Bibliográficos
Autores principales: Li, Mu, Song, Shao-Wei, Ge, Yang, Jin, Jun-Yi, Li, Xiao-Ying, Tan, Xiao-Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7607129/
https://www.ncbi.nlm.nih.gov/pubmed/33178766
http://dx.doi.org/10.21037/atm-20-5880