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Synergistic antitumor activity of a DLL4/VEGF bispecific therapeutic antibody in combination with irinotecan in gastric cancer

Notch signaling has been identified as a critical pathway in gastric cancer (GC) progression and metastasis, and inhibition of Delta-like ligand 4 (DLL4), a Notch ligand, is suggested as a potent therapeutic approach for GC. Expression of both DLL4 and vascular endothelial growth factor receptor 2 (...

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Detalles Bibliográficos
Autores principales:	Kim, Da-Hyun, Lee, Seul, Kang, Hyeok Gu, Park, Hyun-Woo, Lee, Han-Woong, Kim, Dongin, Yoem, Dong-Hoon, Ahn, Jin-Hyung, Ha, Eunsin, You, Weon-Kyoo, Lee, Sang Hoon, Kim, Seok-Jun, Chun, Kyung-Hee
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Korean Society for Biochemistry and Molecular Biology 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7607148/ https://www.ncbi.nlm.nih.gov/pubmed/32580836 http://dx.doi.org/10.5483/BMBRep.2020.53.10.103

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