N-Adamantyl-4-methylthiazol-2-amine suppresses glutamate-induced autophagic cell death via PI3K/Akt/mTOR signaling pathways in cortical neurons

We recently reported that N-adamantyl-4-methylthiazol-2-amine (KHG26693) attenuates glutamate-induced oxidative stress and inflammation in the brain. In this study, we investigated KHG 26693 as a therapeutic agent against glutamate-induced autophagic death of cortical neurons. Treatment with KHG2669...

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Detalles Bibliográficos
Autores principales: Yang, Seung-Ju, Han, A Reum, Choi, Hye-Rim, Hwang, Kyouk, Kim, Eun-A, Choi, Soo Young, Cho, Sung-Woo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7607153/
https://www.ncbi.nlm.nih.gov/pubmed/32635984
http://dx.doi.org/10.5483/BMBRep.2020.53.10.059

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