Cargando…

Cardiotoxicity induced by the combination therapy of chloroquine and azithromycin in human embryonic stem cell-derived cardiomyocytes

Combination therapy using chloroquine (CQ) and azithromycin (AZM) has drawn great attention due to its potential anti-viral activity against SARS-CoV-2. However, clinical trials have revealed that the co-administration of CQ and AZM resulted in severe side effects, including cardiac arrhythmia, in p...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kim, Ye Seul, Lee, Soo Yong, Yoon, Jung Won, Kim, Dasol, Yu, Sangbin, Kim, Jeong Su, Kim, Jae Ho
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Korean Society for Biochemistry and Molecular Biology 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7607154/ https://www.ncbi.nlm.nih.gov/pubmed/32958120 http://dx.doi.org/10.5483/BMBRep.2020.53.10.165

Ejemplares similares

Development and evaluation of next-generation cardiotoxicity assay based on embryonic stem cell-derived cardiomyocytes
por: Ryu, Bokyeong, et al.
Publicado: (2020)

Tomatidine-stimulated maturation of human embryonic stem cell-derived cardiomyocytes for modeling mitochondrial dysfunction
por: Kim, Ye Seul, et al.
Publicado: (2022)

Characterization of the molecular mechanisms underlying azithromycin‐induced cardiotoxicity using human‐induced pluripotent stem cell‐derived cardiomyocytes
por: Wang, Xiaochen, et al.
Publicado: (2021)

Functional expression and pharmaceutical efficacy of cardiac-specific ion channels in human embryonic stem cell-derived cardiomyocytes
por: Kim, Han Sol, et al.
Publicado: (2017)

CAUTION WITH CHLOROQUINE: A CASE OF CHLOROQUINE CARDIOTOXICITY
por: Pelter, Megan, et al.
Publicado: (2023)

Cardiotoxicity evaluation using human embryonic stem cells and induced pluripotent stem cell-derived cardiomyocytes
por: Zhao, Qi, et al.
Publicado: (2017)

Hydroxychloroquine or chloroquine +/- azithromycin: heart disorders
Publicado: (2022)

Virulence factors released from Porphyromonas gingivalis induce electrophysiological dysfunction in human pluripotent stem cell-derived cardiomyocytes
por: Heo, Soon Chul, et al.
Publicado: (2022)

Modeling Doxorubicin-Induced Cardiotoxicity in Human Pluripotent Stem Cell Derived-Cardiomyocytes
por: Maillet, Agnes, et al.
Publicado: (2016)

Chloroquine Cardiotoxicity Leading to Cardiogenic Shock
por: Alder, Madeleine, et al.
Publicado: (2020)

Summary of adverse drug events for hydroxychloroquine, azithromycin, and chloroquine during the COVID-19 pandemic
por: Dauner, Daniel G., et al.
Publicado: (2021)

Cell Therapy with Embryonic Stem Cell-Derived Cardiomyocytes Encapsulated in Injectable Nanomatrix Gel Enhances Cell Engraftment and Promotes Cardiac Repair
por: Ban, Kiwon, et al.
Publicado: (2014)

Echinochrome A Protects Mitochondrial Function in Cardiomyocytes against Cardiotoxic Drugs
por: Jeong, Seung Hun, et al.
Publicado: (2014)

Epigenetic Regulation of Cardiomyocyte Differentiation from Embryonic and Induced Pluripotent Stem Cells
por: Kim, Yong-Jin, et al.
Publicado: (2021)

Cardiotoxicity of chloroquine and hydroxychloroquine through mitochondrial pathway
por: Seydi, Enayatollah, et al.
Publicado: (2023)

Azithromycin-chloroquine and the intermittent preventive treatment of malaria in pregnancy
por: Chico, R Matthew, et al.
Publicado: (2008)

Azithromycin/chloroquine/tacrolimus: Cardiac disorders: case report
Publicado: (2021)

Pharmacometric and Electrocardiographic Evaluation of Chloroquine and Azithromycin in Healthy Volunteers
por: Chotsiri, Palang, et al.
Publicado: (2022)

Population pharmacokinetics of azithromycin and chloroquine in healthy adults and paediatric malaria subjects following oral administration of fixed-dose azithromycin and chloroquine combination tablets
por: Zhao, Qinying, et al.
Publicado: (2014)

Modelling cadmium‐induced cardiotoxicity using human pluripotent stem cell‐derived cardiomyocytes
por: Shen, Jiaxi, et al.
Publicado: (2018)

Chloroquine or Hydroxychloroquine for COVID‐19: Is Cardiotoxicity a Concern?
por: Kamp, Timothy J., et al.
Publicado: (2020)

Electrophysiological properties and calcium handling of embryonic stem cell-derived cardiomyocytes
por: Youm, Jae Boum
Publicado: (2016)

Cardiotoxicity of Antineoplastic Therapies and Applications of Induced Pluripotent Stem Cell-Derived Cardiomyocytes
por: Huang, Mo-Fan, et al.
Publicado: (2021)

Oral Azithromycin for Treatment of Intractable Rosacea
por: Kim, Jae-Hong, et al.
Publicado: (2011)

Next-Generation Intestinal Toxicity Model of Human Embryonic Stem Cell-Derived Enterocyte-Like Cells
por: Ryu, Bokyeong, et al.
Publicado: (2021)

Electrophysiological mechanisms of vandetanib-induced cardiotoxicity: Comparison of action potentials in rabbit Purkinje fibers and pluripotent stem cell-derived cardiomyocytes
por: Lee, Hyang-Ae, et al.
Publicado: (2018)

Human Pluripotent Stem Cell-Derived Cardiomyocytes for Assessment of Anticancer Drug-Induced Cardiotoxicity
por: Schwach, Verena, et al.
Publicado: (2020)

Liensinine- and Neferine-Induced Cardiotoxicity in Primary Neonatal Rat Cardiomyocytes and Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes
por: Yu, Yangyang, et al.
Publicado: (2016)

Role of the epithelial–mesenchymal transition and its effects on embryonic stem cells
por: Kim, Ye-Seul, et al.
Publicado: (2014)

Mitochondrial pyruvate dehydrogenase phosphatase 1 regulates the early differentiation of cardiomyocytes from mouse embryonic stem cells
por: Heo, Hye Jin, et al.
Publicado: (2016)

Therapeutic Strategies for Targeting Ovarian Cancer Stem Cells
por: Yang, Wookyeom, et al.
Publicado: (2021)

Non-genetic Purification of Ventricular Cardiomyocytes from Differentiating Embryonic Stem Cells through Molecular Beacons Targeting IRX-4
por: Ban, Kiwon, et al.
Publicado: (2015)

Circadian networks in human embryonic stem cell‐derived cardiomyocytes
por: Dierickx, Pieterjan, et al.
Publicado: (2017)

Automated image analysis system for studying cardiotoxicity in human pluripotent stem cell-Derived cardiomyocytes
por: Cao, Lu, et al.
Publicado: (2020)

Treatment of adults with acute uncomplicated malaria with azithromycin and chloroquine in India, Colombia, and Suriname
por: Kshirsagar, Nilima A, et al.
Publicado: (2017)

Beta-Adrenergic Receptor Stimulation Modulates the Cellular Proarrhythmic Effects of Chloroquine and Azithromycin
por: Sutanto, Henry, et al.
Publicado: (2020)

Azithromycin and ciprofloxacin have a chloroquine-like effect on respiratory epithelial cells
por: Poschet, Jens F., et al.
Publicado: (2020)

Hydroxychloroquine/chloroquine and azithromycin in COVID-19 patients: prospective study of electrical parameters
por: Ammor, Othmane, et al.
Publicado: (2021)

Prevention and treatment of COVID-19: Focus on interferons, chloroquine/hydroxychloroquine, azithromycin, and vaccine
por: Bakadia, Bianza Moise, et al.
Publicado: (2021)

Lysosomotropic agents including azithromycin, chloroquine and hydroxychloroquine activate the integrated stress response
por: Tian, Ai-Ling, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_4ubist5qk6ffuhm186q9gpq536