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Effects of dasatinib on CD8(+)T, Th1, and Treg cells in patients with chronic myeloid leukemia

OBJECTIVE: To investigate the immunomodulatory effects of the tyrosine kinase inhibitor (TKI) dasatinib on T-cell subtypes in patients with chronic myeloid leukemia (CML). METHODS: T helper (Th) 1, Th2, regulatory T (Treg), and CD8(+)T cell levels were detected in patients with CML (n = 9) before an...

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Detalles Bibliográficos
Autores principales: Wei, Xiaoqing, He, Lin, Wang, Xiaodong, Lin, Min, Dai, Jingying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7607186/
https://www.ncbi.nlm.nih.gov/pubmed/31578901
http://dx.doi.org/10.1177/0300060519877321