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Transcription Factor Binding Affinities and DNA Shape Readout

An essential event in gene regulation is the binding of a transcription factor (TF) to its target DNA. Models considering the interactions between the TF and the DNA geometry proved to be successful approaches to describe this binding event, while conserving data interpretability. However, a direct...

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Detalles Bibliográficos
Autores principales: Schnepf, Max, von Reutern, Marc, Ludwig, Claudia, Jung, Christophe, Gaul, Ulrike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7607496/
https://www.ncbi.nlm.nih.gov/pubmed/33163946
http://dx.doi.org/10.1016/j.isci.2020.101694