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Transcription Factor Binding Affinities and DNA Shape Readout
An essential event in gene regulation is the binding of a transcription factor (TF) to its target DNA. Models considering the interactions between the TF and the DNA geometry proved to be successful approaches to describe this binding event, while conserving data interpretability. However, a direct...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7607496/ https://www.ncbi.nlm.nih.gov/pubmed/33163946 http://dx.doi.org/10.1016/j.isci.2020.101694 |