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Controlled Heat and Humidity-Based Treatment for the Reuse of Personal Protective Equipment: A Pragmatic Proof-of-Concept to Address the Mass Shortage of Surgical Masks and N95/FFP2 Respirators and to Prevent the SARS-CoV2 Transmission

Background: The coronavirus infectious disease-2019 (COVID-19) pandemic has led to an unprecedented shortage of healthcare resources, primarily personal protective equipment like surgical masks, and N95/filtering face piece type 2 (FFP2) respirators. Objective: Reuse of surgical masks and N95/FFP2 r...

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Autores principales: Bernard, Louis, Desoubeaux, Guillaume, Bodier-Montagutelli, Elsa, Pardessus, Jeoffrey, Brea, Déborah, Allimonnier, Laurine, Eymieux, Sébastien, Raynal, Pierre-Ivan, Vasseur, Virginie, Vecellio, Laurent, Mathé, Ludovic, Guillon, Antoine, Lanotte, Philippe, Pourchez, Jérémie, Verhoeven, Paul O., Esnouf, Stéphane, Ferry, Muriel, Eterradossi, Nicolas, Blanchard, Yannick, Brown, Paul, Roingeard, Philippe, Alcaraz, Jean-Pierre, Cinquin, Philippe, Si-Tahar, Mustapha, Heuzé-Vourc'h, Nathalie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7607499/
https://www.ncbi.nlm.nih.gov/pubmed/33195335
http://dx.doi.org/10.3389/fmed.2020.584036
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author Bernard, Louis
Desoubeaux, Guillaume
Bodier-Montagutelli, Elsa
Pardessus, Jeoffrey
Brea, Déborah
Allimonnier, Laurine
Eymieux, Sébastien
Raynal, Pierre-Ivan
Vasseur, Virginie
Vecellio, Laurent
Mathé, Ludovic
Guillon, Antoine
Lanotte, Philippe
Pourchez, Jérémie
Verhoeven, Paul O.
Esnouf, Stéphane
Ferry, Muriel
Eterradossi, Nicolas
Blanchard, Yannick
Brown, Paul
Roingeard, Philippe
Alcaraz, Jean-Pierre
Cinquin, Philippe
Si-Tahar, Mustapha
Heuzé-Vourc'h, Nathalie
author_facet Bernard, Louis
Desoubeaux, Guillaume
Bodier-Montagutelli, Elsa
Pardessus, Jeoffrey
Brea, Déborah
Allimonnier, Laurine
Eymieux, Sébastien
Raynal, Pierre-Ivan
Vasseur, Virginie
Vecellio, Laurent
Mathé, Ludovic
Guillon, Antoine
Lanotte, Philippe
Pourchez, Jérémie
Verhoeven, Paul O.
Esnouf, Stéphane
Ferry, Muriel
Eterradossi, Nicolas
Blanchard, Yannick
Brown, Paul
Roingeard, Philippe
Alcaraz, Jean-Pierre
Cinquin, Philippe
Si-Tahar, Mustapha
Heuzé-Vourc'h, Nathalie
author_sort Bernard, Louis
collection PubMed
description Background: The coronavirus infectious disease-2019 (COVID-19) pandemic has led to an unprecedented shortage of healthcare resources, primarily personal protective equipment like surgical masks, and N95/filtering face piece type 2 (FFP2) respirators. Objective: Reuse of surgical masks and N95/FFP2 respirators may circumvent the supply chain constraints and thus overcome mass shortage. Methods, design, setting, and measurement: Herein, we tested the effects of dry- and moist-air controlled heating treatment on structure and chemical integrity, decontamination yield, and filtration performance of surgical masks and FFP2 respirators. Results: We found that treatment in a climate chamber at 70°C during 1 h with 75% humidity rate was adequate for enabling substantial decontamination of both respiratory viruses, oropharyngeal bacteria, and model animal coronaviuses, while maintaining a satisfying filtering capacity. Limitations: Further studies are now required to confirm the feasibility of the whole process during routine practice. Conclusion: Our findings provide compelling evidence for the recycling of pre-used surgical masks and N95/FFP2 respirators in case of imminent mass shortfall.
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spelling pubmed-76074992020-11-13 Controlled Heat and Humidity-Based Treatment for the Reuse of Personal Protective Equipment: A Pragmatic Proof-of-Concept to Address the Mass Shortage of Surgical Masks and N95/FFP2 Respirators and to Prevent the SARS-CoV2 Transmission Bernard, Louis Desoubeaux, Guillaume Bodier-Montagutelli, Elsa Pardessus, Jeoffrey Brea, Déborah Allimonnier, Laurine Eymieux, Sébastien Raynal, Pierre-Ivan Vasseur, Virginie Vecellio, Laurent Mathé, Ludovic Guillon, Antoine Lanotte, Philippe Pourchez, Jérémie Verhoeven, Paul O. Esnouf, Stéphane Ferry, Muriel Eterradossi, Nicolas Blanchard, Yannick Brown, Paul Roingeard, Philippe Alcaraz, Jean-Pierre Cinquin, Philippe Si-Tahar, Mustapha Heuzé-Vourc'h, Nathalie Front Med (Lausanne) Medicine Background: The coronavirus infectious disease-2019 (COVID-19) pandemic has led to an unprecedented shortage of healthcare resources, primarily personal protective equipment like surgical masks, and N95/filtering face piece type 2 (FFP2) respirators. Objective: Reuse of surgical masks and N95/FFP2 respirators may circumvent the supply chain constraints and thus overcome mass shortage. Methods, design, setting, and measurement: Herein, we tested the effects of dry- and moist-air controlled heating treatment on structure and chemical integrity, decontamination yield, and filtration performance of surgical masks and FFP2 respirators. Results: We found that treatment in a climate chamber at 70°C during 1 h with 75% humidity rate was adequate for enabling substantial decontamination of both respiratory viruses, oropharyngeal bacteria, and model animal coronaviuses, while maintaining a satisfying filtering capacity. Limitations: Further studies are now required to confirm the feasibility of the whole process during routine practice. Conclusion: Our findings provide compelling evidence for the recycling of pre-used surgical masks and N95/FFP2 respirators in case of imminent mass shortfall. Frontiers Media S.A. 2020-10-20 /pmc/articles/PMC7607499/ /pubmed/33195335 http://dx.doi.org/10.3389/fmed.2020.584036 Text en Copyright © 2020 Bernard, Desoubeaux, Bodier-Montagutelli, Pardessus, Brea, Allimonnier, Eymieux, Raynal, Vasseur, Vecellio, Mathé, Guillon, Lanotte, Pourchez, Verhoeven, Esnouf, Ferry, Eterradossi, Blanchard, Brown, Roingeard, Alcaraz, Cinquin, Si-Tahar and Heuzé-Vourc'h. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Medicine
Bernard, Louis
Desoubeaux, Guillaume
Bodier-Montagutelli, Elsa
Pardessus, Jeoffrey
Brea, Déborah
Allimonnier, Laurine
Eymieux, Sébastien
Raynal, Pierre-Ivan
Vasseur, Virginie
Vecellio, Laurent
Mathé, Ludovic
Guillon, Antoine
Lanotte, Philippe
Pourchez, Jérémie
Verhoeven, Paul O.
Esnouf, Stéphane
Ferry, Muriel
Eterradossi, Nicolas
Blanchard, Yannick
Brown, Paul
Roingeard, Philippe
Alcaraz, Jean-Pierre
Cinquin, Philippe
Si-Tahar, Mustapha
Heuzé-Vourc'h, Nathalie
Controlled Heat and Humidity-Based Treatment for the Reuse of Personal Protective Equipment: A Pragmatic Proof-of-Concept to Address the Mass Shortage of Surgical Masks and N95/FFP2 Respirators and to Prevent the SARS-CoV2 Transmission
title Controlled Heat and Humidity-Based Treatment for the Reuse of Personal Protective Equipment: A Pragmatic Proof-of-Concept to Address the Mass Shortage of Surgical Masks and N95/FFP2 Respirators and to Prevent the SARS-CoV2 Transmission
title_full Controlled Heat and Humidity-Based Treatment for the Reuse of Personal Protective Equipment: A Pragmatic Proof-of-Concept to Address the Mass Shortage of Surgical Masks and N95/FFP2 Respirators and to Prevent the SARS-CoV2 Transmission
title_fullStr Controlled Heat and Humidity-Based Treatment for the Reuse of Personal Protective Equipment: A Pragmatic Proof-of-Concept to Address the Mass Shortage of Surgical Masks and N95/FFP2 Respirators and to Prevent the SARS-CoV2 Transmission
title_full_unstemmed Controlled Heat and Humidity-Based Treatment for the Reuse of Personal Protective Equipment: A Pragmatic Proof-of-Concept to Address the Mass Shortage of Surgical Masks and N95/FFP2 Respirators and to Prevent the SARS-CoV2 Transmission
title_short Controlled Heat and Humidity-Based Treatment for the Reuse of Personal Protective Equipment: A Pragmatic Proof-of-Concept to Address the Mass Shortage of Surgical Masks and N95/FFP2 Respirators and to Prevent the SARS-CoV2 Transmission
title_sort controlled heat and humidity-based treatment for the reuse of personal protective equipment: a pragmatic proof-of-concept to address the mass shortage of surgical masks and n95/ffp2 respirators and to prevent the sars-cov2 transmission
topic Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7607499/
https://www.ncbi.nlm.nih.gov/pubmed/33195335
http://dx.doi.org/10.3389/fmed.2020.584036
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