Cargando…
Controlled Heat and Humidity-Based Treatment for the Reuse of Personal Protective Equipment: A Pragmatic Proof-of-Concept to Address the Mass Shortage of Surgical Masks and N95/FFP2 Respirators and to Prevent the SARS-CoV2 Transmission
Background: The coronavirus infectious disease-2019 (COVID-19) pandemic has led to an unprecedented shortage of healthcare resources, primarily personal protective equipment like surgical masks, and N95/filtering face piece type 2 (FFP2) respirators. Objective: Reuse of surgical masks and N95/FFP2 r...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7607499/ https://www.ncbi.nlm.nih.gov/pubmed/33195335 http://dx.doi.org/10.3389/fmed.2020.584036 |
_version_ | 1783604658971869184 |
---|---|
author | Bernard, Louis Desoubeaux, Guillaume Bodier-Montagutelli, Elsa Pardessus, Jeoffrey Brea, Déborah Allimonnier, Laurine Eymieux, Sébastien Raynal, Pierre-Ivan Vasseur, Virginie Vecellio, Laurent Mathé, Ludovic Guillon, Antoine Lanotte, Philippe Pourchez, Jérémie Verhoeven, Paul O. Esnouf, Stéphane Ferry, Muriel Eterradossi, Nicolas Blanchard, Yannick Brown, Paul Roingeard, Philippe Alcaraz, Jean-Pierre Cinquin, Philippe Si-Tahar, Mustapha Heuzé-Vourc'h, Nathalie |
author_facet | Bernard, Louis Desoubeaux, Guillaume Bodier-Montagutelli, Elsa Pardessus, Jeoffrey Brea, Déborah Allimonnier, Laurine Eymieux, Sébastien Raynal, Pierre-Ivan Vasseur, Virginie Vecellio, Laurent Mathé, Ludovic Guillon, Antoine Lanotte, Philippe Pourchez, Jérémie Verhoeven, Paul O. Esnouf, Stéphane Ferry, Muriel Eterradossi, Nicolas Blanchard, Yannick Brown, Paul Roingeard, Philippe Alcaraz, Jean-Pierre Cinquin, Philippe Si-Tahar, Mustapha Heuzé-Vourc'h, Nathalie |
author_sort | Bernard, Louis |
collection | PubMed |
description | Background: The coronavirus infectious disease-2019 (COVID-19) pandemic has led to an unprecedented shortage of healthcare resources, primarily personal protective equipment like surgical masks, and N95/filtering face piece type 2 (FFP2) respirators. Objective: Reuse of surgical masks and N95/FFP2 respirators may circumvent the supply chain constraints and thus overcome mass shortage. Methods, design, setting, and measurement: Herein, we tested the effects of dry- and moist-air controlled heating treatment on structure and chemical integrity, decontamination yield, and filtration performance of surgical masks and FFP2 respirators. Results: We found that treatment in a climate chamber at 70°C during 1 h with 75% humidity rate was adequate for enabling substantial decontamination of both respiratory viruses, oropharyngeal bacteria, and model animal coronaviuses, while maintaining a satisfying filtering capacity. Limitations: Further studies are now required to confirm the feasibility of the whole process during routine practice. Conclusion: Our findings provide compelling evidence for the recycling of pre-used surgical masks and N95/FFP2 respirators in case of imminent mass shortfall. |
format | Online Article Text |
id | pubmed-7607499 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-76074992020-11-13 Controlled Heat and Humidity-Based Treatment for the Reuse of Personal Protective Equipment: A Pragmatic Proof-of-Concept to Address the Mass Shortage of Surgical Masks and N95/FFP2 Respirators and to Prevent the SARS-CoV2 Transmission Bernard, Louis Desoubeaux, Guillaume Bodier-Montagutelli, Elsa Pardessus, Jeoffrey Brea, Déborah Allimonnier, Laurine Eymieux, Sébastien Raynal, Pierre-Ivan Vasseur, Virginie Vecellio, Laurent Mathé, Ludovic Guillon, Antoine Lanotte, Philippe Pourchez, Jérémie Verhoeven, Paul O. Esnouf, Stéphane Ferry, Muriel Eterradossi, Nicolas Blanchard, Yannick Brown, Paul Roingeard, Philippe Alcaraz, Jean-Pierre Cinquin, Philippe Si-Tahar, Mustapha Heuzé-Vourc'h, Nathalie Front Med (Lausanne) Medicine Background: The coronavirus infectious disease-2019 (COVID-19) pandemic has led to an unprecedented shortage of healthcare resources, primarily personal protective equipment like surgical masks, and N95/filtering face piece type 2 (FFP2) respirators. Objective: Reuse of surgical masks and N95/FFP2 respirators may circumvent the supply chain constraints and thus overcome mass shortage. Methods, design, setting, and measurement: Herein, we tested the effects of dry- and moist-air controlled heating treatment on structure and chemical integrity, decontamination yield, and filtration performance of surgical masks and FFP2 respirators. Results: We found that treatment in a climate chamber at 70°C during 1 h with 75% humidity rate was adequate for enabling substantial decontamination of both respiratory viruses, oropharyngeal bacteria, and model animal coronaviuses, while maintaining a satisfying filtering capacity. Limitations: Further studies are now required to confirm the feasibility of the whole process during routine practice. Conclusion: Our findings provide compelling evidence for the recycling of pre-used surgical masks and N95/FFP2 respirators in case of imminent mass shortfall. Frontiers Media S.A. 2020-10-20 /pmc/articles/PMC7607499/ /pubmed/33195335 http://dx.doi.org/10.3389/fmed.2020.584036 Text en Copyright © 2020 Bernard, Desoubeaux, Bodier-Montagutelli, Pardessus, Brea, Allimonnier, Eymieux, Raynal, Vasseur, Vecellio, Mathé, Guillon, Lanotte, Pourchez, Verhoeven, Esnouf, Ferry, Eterradossi, Blanchard, Brown, Roingeard, Alcaraz, Cinquin, Si-Tahar and Heuzé-Vourc'h. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Medicine Bernard, Louis Desoubeaux, Guillaume Bodier-Montagutelli, Elsa Pardessus, Jeoffrey Brea, Déborah Allimonnier, Laurine Eymieux, Sébastien Raynal, Pierre-Ivan Vasseur, Virginie Vecellio, Laurent Mathé, Ludovic Guillon, Antoine Lanotte, Philippe Pourchez, Jérémie Verhoeven, Paul O. Esnouf, Stéphane Ferry, Muriel Eterradossi, Nicolas Blanchard, Yannick Brown, Paul Roingeard, Philippe Alcaraz, Jean-Pierre Cinquin, Philippe Si-Tahar, Mustapha Heuzé-Vourc'h, Nathalie Controlled Heat and Humidity-Based Treatment for the Reuse of Personal Protective Equipment: A Pragmatic Proof-of-Concept to Address the Mass Shortage of Surgical Masks and N95/FFP2 Respirators and to Prevent the SARS-CoV2 Transmission |
title | Controlled Heat and Humidity-Based Treatment for the Reuse of Personal Protective Equipment: A Pragmatic Proof-of-Concept to Address the Mass Shortage of Surgical Masks and N95/FFP2 Respirators and to Prevent the SARS-CoV2 Transmission |
title_full | Controlled Heat and Humidity-Based Treatment for the Reuse of Personal Protective Equipment: A Pragmatic Proof-of-Concept to Address the Mass Shortage of Surgical Masks and N95/FFP2 Respirators and to Prevent the SARS-CoV2 Transmission |
title_fullStr | Controlled Heat and Humidity-Based Treatment for the Reuse of Personal Protective Equipment: A Pragmatic Proof-of-Concept to Address the Mass Shortage of Surgical Masks and N95/FFP2 Respirators and to Prevent the SARS-CoV2 Transmission |
title_full_unstemmed | Controlled Heat and Humidity-Based Treatment for the Reuse of Personal Protective Equipment: A Pragmatic Proof-of-Concept to Address the Mass Shortage of Surgical Masks and N95/FFP2 Respirators and to Prevent the SARS-CoV2 Transmission |
title_short | Controlled Heat and Humidity-Based Treatment for the Reuse of Personal Protective Equipment: A Pragmatic Proof-of-Concept to Address the Mass Shortage of Surgical Masks and N95/FFP2 Respirators and to Prevent the SARS-CoV2 Transmission |
title_sort | controlled heat and humidity-based treatment for the reuse of personal protective equipment: a pragmatic proof-of-concept to address the mass shortage of surgical masks and n95/ffp2 respirators and to prevent the sars-cov2 transmission |
topic | Medicine |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7607499/ https://www.ncbi.nlm.nih.gov/pubmed/33195335 http://dx.doi.org/10.3389/fmed.2020.584036 |
work_keys_str_mv | AT bernardlouis controlledheatandhumiditybasedtreatmentforthereuseofpersonalprotectiveequipmentapragmaticproofofconcepttoaddressthemassshortageofsurgicalmasksandn95ffp2respiratorsandtopreventthesarscov2transmission AT desoubeauxguillaume controlledheatandhumiditybasedtreatmentforthereuseofpersonalprotectiveequipmentapragmaticproofofconcepttoaddressthemassshortageofsurgicalmasksandn95ffp2respiratorsandtopreventthesarscov2transmission AT bodiermontagutellielsa controlledheatandhumiditybasedtreatmentforthereuseofpersonalprotectiveequipmentapragmaticproofofconcepttoaddressthemassshortageofsurgicalmasksandn95ffp2respiratorsandtopreventthesarscov2transmission AT pardessusjeoffrey controlledheatandhumiditybasedtreatmentforthereuseofpersonalprotectiveequipmentapragmaticproofofconcepttoaddressthemassshortageofsurgicalmasksandn95ffp2respiratorsandtopreventthesarscov2transmission AT breadeborah controlledheatandhumiditybasedtreatmentforthereuseofpersonalprotectiveequipmentapragmaticproofofconcepttoaddressthemassshortageofsurgicalmasksandn95ffp2respiratorsandtopreventthesarscov2transmission AT allimonnierlaurine controlledheatandhumiditybasedtreatmentforthereuseofpersonalprotectiveequipmentapragmaticproofofconcepttoaddressthemassshortageofsurgicalmasksandn95ffp2respiratorsandtopreventthesarscov2transmission AT eymieuxsebastien controlledheatandhumiditybasedtreatmentforthereuseofpersonalprotectiveequipmentapragmaticproofofconcepttoaddressthemassshortageofsurgicalmasksandn95ffp2respiratorsandtopreventthesarscov2transmission AT raynalpierreivan controlledheatandhumiditybasedtreatmentforthereuseofpersonalprotectiveequipmentapragmaticproofofconcepttoaddressthemassshortageofsurgicalmasksandn95ffp2respiratorsandtopreventthesarscov2transmission AT vasseurvirginie controlledheatandhumiditybasedtreatmentforthereuseofpersonalprotectiveequipmentapragmaticproofofconcepttoaddressthemassshortageofsurgicalmasksandn95ffp2respiratorsandtopreventthesarscov2transmission AT vecelliolaurent controlledheatandhumiditybasedtreatmentforthereuseofpersonalprotectiveequipmentapragmaticproofofconcepttoaddressthemassshortageofsurgicalmasksandn95ffp2respiratorsandtopreventthesarscov2transmission AT matheludovic controlledheatandhumiditybasedtreatmentforthereuseofpersonalprotectiveequipmentapragmaticproofofconcepttoaddressthemassshortageofsurgicalmasksandn95ffp2respiratorsandtopreventthesarscov2transmission AT guillonantoine controlledheatandhumiditybasedtreatmentforthereuseofpersonalprotectiveequipmentapragmaticproofofconcepttoaddressthemassshortageofsurgicalmasksandn95ffp2respiratorsandtopreventthesarscov2transmission AT lanottephilippe controlledheatandhumiditybasedtreatmentforthereuseofpersonalprotectiveequipmentapragmaticproofofconcepttoaddressthemassshortageofsurgicalmasksandn95ffp2respiratorsandtopreventthesarscov2transmission AT pourchezjeremie controlledheatandhumiditybasedtreatmentforthereuseofpersonalprotectiveequipmentapragmaticproofofconcepttoaddressthemassshortageofsurgicalmasksandn95ffp2respiratorsandtopreventthesarscov2transmission AT verhoevenpaulo controlledheatandhumiditybasedtreatmentforthereuseofpersonalprotectiveequipmentapragmaticproofofconcepttoaddressthemassshortageofsurgicalmasksandn95ffp2respiratorsandtopreventthesarscov2transmission AT esnoufstephane controlledheatandhumiditybasedtreatmentforthereuseofpersonalprotectiveequipmentapragmaticproofofconcepttoaddressthemassshortageofsurgicalmasksandn95ffp2respiratorsandtopreventthesarscov2transmission AT ferrymuriel controlledheatandhumiditybasedtreatmentforthereuseofpersonalprotectiveequipmentapragmaticproofofconcepttoaddressthemassshortageofsurgicalmasksandn95ffp2respiratorsandtopreventthesarscov2transmission AT eterradossinicolas controlledheatandhumiditybasedtreatmentforthereuseofpersonalprotectiveequipmentapragmaticproofofconcepttoaddressthemassshortageofsurgicalmasksandn95ffp2respiratorsandtopreventthesarscov2transmission AT blanchardyannick controlledheatandhumiditybasedtreatmentforthereuseofpersonalprotectiveequipmentapragmaticproofofconcepttoaddressthemassshortageofsurgicalmasksandn95ffp2respiratorsandtopreventthesarscov2transmission AT brownpaul controlledheatandhumiditybasedtreatmentforthereuseofpersonalprotectiveequipmentapragmaticproofofconcepttoaddressthemassshortageofsurgicalmasksandn95ffp2respiratorsandtopreventthesarscov2transmission AT roingeardphilippe controlledheatandhumiditybasedtreatmentforthereuseofpersonalprotectiveequipmentapragmaticproofofconcepttoaddressthemassshortageofsurgicalmasksandn95ffp2respiratorsandtopreventthesarscov2transmission AT alcarazjeanpierre controlledheatandhumiditybasedtreatmentforthereuseofpersonalprotectiveequipmentapragmaticproofofconcepttoaddressthemassshortageofsurgicalmasksandn95ffp2respiratorsandtopreventthesarscov2transmission AT cinquinphilippe controlledheatandhumiditybasedtreatmentforthereuseofpersonalprotectiveequipmentapragmaticproofofconcepttoaddressthemassshortageofsurgicalmasksandn95ffp2respiratorsandtopreventthesarscov2transmission AT sitaharmustapha controlledheatandhumiditybasedtreatmentforthereuseofpersonalprotectiveequipmentapragmaticproofofconcepttoaddressthemassshortageofsurgicalmasksandn95ffp2respiratorsandtopreventthesarscov2transmission AT heuzevourchnathalie controlledheatandhumiditybasedtreatmentforthereuseofpersonalprotectiveequipmentapragmaticproofofconcepttoaddressthemassshortageofsurgicalmasksandn95ffp2respiratorsandtopreventthesarscov2transmission |