In vitro-induction of metronidazole-resistant Giardia duodenalis is not associated with nucleotide alterations in the genes involved in pro-drug activation

Giardiasis is an infectious disease caused by Giardia duodenalis. The pro-drug metronidazole (MTZ) is the first-line treatment for giardiasis. Parasite’s proteins as pyruvate:ferredoxin oxidoreductase (PFOR), ferredoxin (Fd), nitroreductase-1 (NR-1) and thioredoxin reductase (TrxR) participate in MT...

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Detalles Bibliográficos
Autores principales: Lopes-Oliveira, Luiz Antonio Pimentel, Fantinatti, Maria, Da-Cruz, Alda Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Instituto Oswaldo Cruz, Ministério da Saúde 2020
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7607557/
https://www.ncbi.nlm.nih.gov/pubmed/33146255
http://dx.doi.org/10.1590/0074-02760200303

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7607557/
https://www.ncbi.nlm.nih.gov/pubmed/33146255
http://dx.doi.org/10.1590/0074-02760200303

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