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Pancreatic GLP-1r binding potential is reduced in insulin-resistant pigs

INTRODUCTION: The insulinotropic capacity of exogenous glucagon like peptide-1 (GLP-1) is reduced in type 2 diabetes and the insulin-resistant obese. We have tested the hypothesis that this response is the consequence of a reduced pancreatic GLP-1 receptor (GLP-1r) density in insulin-resistant obese...

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Detalles Bibliográficos
Autores principales:	Malbert, Charles-Henri, Chauvin, Alain, Horowitz, Michael, Jones, Karen L
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2020
Materias:	Obesity Studies
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7607594/ https://www.ncbi.nlm.nih.gov/pubmed/33132211 http://dx.doi.org/10.1136/bmjdrc-2020-001540

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