Lonidamine potentiates the oncolytic efficiency of M1 virus independent of hexokinase 2 but via inhibition of antiviral immunity

BACKGROUND: Viruses are obligate parasites that depend on host cells to provide the energy and molecular precursors necessary for successful infection. The main component of virus-induced metabolic reprogramming is the activation of glycolysis, which provides biomolecular resources for viral replica...

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Detalles Bibliográficos
Autores principales: Cai, Jing, Zhu, Wenbo, Lin, Yuan, Hu, Jun, Liu, Xincheng, Xu, Wencang, Liu, Ying, Hu, Cheng, He, Songmin, Gong, Shoufang, Yan, Guangmei, Liang, Jiankai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Primary Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7607643/
https://www.ncbi.nlm.nih.gov/pubmed/33292203
http://dx.doi.org/10.1186/s12935-020-01598-w

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