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miRNA-126-3p carried by human umbilical cord mesenchymal stem cell enhances endothelial function through exosome-mediated mechanisms in vitro and attenuates vein graft neointimal formation in vivo

BACKGROUND: The aim of this study was to determine whether the combination of MSC implantation with miRNA-126-3p overexpression would further improve the surgical results after vein grafting. METHODS: human umbilical cord MSCs (hucMSCs) and human umbilical vein endothelial cells (HUVECs) were isolat...

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Detalles Bibliográficos
Autores principales:	Qu, Qingxi, Wang, Limei, Bing, Weidong, Bi, Yanwen, Zhang, Chunmei, Jing, Xuanxuan, Liu, Linghong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7607661/ https://www.ncbi.nlm.nih.gov/pubmed/33138861 http://dx.doi.org/10.1186/s13287-020-01978-z

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