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Intelligent microbial cell factory with genetic pH shooting (GPS) for cell self-responsive base/acid regulation

BACKGROUND: In industrial fermentation, pH fluctuation resulted from microbial metabolism influences the strain performance and the final production. The common way to control pH is adding acid or alkali after probe detection, which is not a fine-tuned method and often leads to increased costs and c...

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Detalles Bibliográficos
Autores principales: Li, Chenyi, Gao, Xiaopeng, Peng, Xiao, Li, Jinlin, Bai, Wenxin, Zhong, Jiadong, He, Mengchao, Xu, Ke, Wang, Ying, Li, Chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7607686/
https://www.ncbi.nlm.nih.gov/pubmed/33138821
http://dx.doi.org/10.1186/s12934-020-01457-3