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Intelligent microbial cell factory with genetic pH shooting (GPS) for cell self-responsive base/acid regulation
BACKGROUND: In industrial fermentation, pH fluctuation resulted from microbial metabolism influences the strain performance and the final production. The common way to control pH is adding acid or alkali after probe detection, which is not a fine-tuned method and often leads to increased costs and c...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7607686/ https://www.ncbi.nlm.nih.gov/pubmed/33138821 http://dx.doi.org/10.1186/s12934-020-01457-3 |