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The anti-scarring effect of corneal stromal stem cell therapy is mediated by transforming growth factor β3

BACKGROUND: Corneal stromal stem cells (CSSC) reduce corneal inflammation, prevent fibrotic scarring, and regenerate transparent stromal tissue in injured corneas. These effects rely on factors produced by CSSC to block the fibrotic gene expression. This study investigated the mechanism of the scar-...

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Detalles Bibliográficos
Autores principales: Weng, Lin, Funderburgh, James L., Khandaker, Irona, Geary, Moira L., Yang, Tianbing, Basu, Rohan, Funderburgh, Martha L., Du, Yiqin, Yam, Gary Hin-Fai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7607765/
https://www.ncbi.nlm.nih.gov/pubmed/33292650
http://dx.doi.org/10.1186/s40662-020-00217-z