Mutation screening of germline TP53 mutations in high-risk Chinese breast cancer patients

BACKGROUND: Germline TP53 mutations are associated with Li-Fraumeni syndrome, a severe and rare hereditary cancer syndrome. Despite the rarity of germline TP53 mutations, the clinical implication for mutation carriers and their families is significant. The risk management of TP53 germline mutation c...

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Detalles Bibliográficos
Autores principales: Kwong, Ava, Shin, Vivian Yvonne, Ho, Cecilia Y. S., Au, Chun Hang, Slavin, Thomas P., Weitzel, Jeffrey N., Chan, Tsun-Leung, Ma, Edmond S. K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7607817/
https://www.ncbi.nlm.nih.gov/pubmed/33138793
http://dx.doi.org/10.1186/s12885-020-07476-y

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