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Functional analysis of bovine interleukin-10 receptor alpha in response to Mycobacterium avium subsp. paratuberculosis lysate using CRISPR/Cas9

BACKGROUND: The interleukin-10 receptor alpha (IL10RA) gene codes for the alpha chain of the IL-10 receptor which binds the cytokine IL-10. IL-10 is an anti-inflammatory cytokine with immunoregulatory function during the pathogenesis of many inflammatory disorders in livestock, including Johne’s dis...

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Detalles Bibliográficos
Autores principales:	Mallikarjunappa, Sanjay, Shandilya, Umesh K., Sharma, Ankita, Lamers, Kristen, Bissonnette, Nathalie, Karrow, Niel A., Meade, Kieran G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7607837/ https://www.ncbi.nlm.nih.gov/pubmed/33138773 http://dx.doi.org/10.1186/s12863-020-00925-4

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