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Anti-tumor efficacy of CKD-516 in combination with radiation in xenograft mouse model of lung squamous cell carcinoma

BACKGROUND: Hypoxic tumors are known to be highly resistant to radiotherapy and cause poor prognosis in non-small cell lung cancer (NSCLC) patients. CKD-516, a novel vascular disrupting agent (VDA), mainly affects blood vessels in the central area of the tumor and blocks tubulin polymerization, ther...

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Detalles Bibliográficos
Autores principales:	Kim, Min-Young, Shin, Jung-Young, Kim, Jeong-Oh, Son, Kyoung-Hwa, Kim, Yeon Sil, Jung, Chan Kwon, Kang, Jin-Hyoung
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7607852/ https://www.ncbi.nlm.nih.gov/pubmed/33143663 http://dx.doi.org/10.1186/s12885-020-07566-x

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