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Unexpected high platelet counts in a potential platelet donor: A clue to essential thrombocythemia
Essential thrombocythemia (ET) (primary thrombocythemia) is a nonreactive, chronic myeloproliferative clonal disorder in which sustained megakaryocyte proliferation leads to an increase in the number of circulating platelets. It is silent disorder and is diagnosed as high platelet counts with or wit...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer - Medknow
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7607989/ https://www.ncbi.nlm.nih.gov/pubmed/33162716 http://dx.doi.org/10.4103/ajts.AJTS_114_19 |
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author | Navkudkar, Anisha Desai, Priti Rajadhyaksha, Sunil |
author_facet | Navkudkar, Anisha Desai, Priti Rajadhyaksha, Sunil |
author_sort | Navkudkar, Anisha |
collection | PubMed |
description | Essential thrombocythemia (ET) (primary thrombocythemia) is a nonreactive, chronic myeloproliferative clonal disorder in which sustained megakaryocyte proliferation leads to an increase in the number of circulating platelets. It is silent disorder and is diagnosed as high platelet counts with or without associated symptoms or as an accidental finding. We, hereby, report a case of ET as an incidental finding during screening of a potential platelet donor. Donors with high platelet count should be investigated properly to rule out ET. The role of transfusion medicine specialist is not only to recruit donors but also to identify such donors during screening and counsel them for detailed investigation and proper management. |
format | Online Article Text |
id | pubmed-7607989 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Wolters Kluwer - Medknow |
record_format | MEDLINE/PubMed |
spelling | pubmed-76079892020-11-05 Unexpected high platelet counts in a potential platelet donor: A clue to essential thrombocythemia Navkudkar, Anisha Desai, Priti Rajadhyaksha, Sunil Asian J Transfus Sci Case Report Essential thrombocythemia (ET) (primary thrombocythemia) is a nonreactive, chronic myeloproliferative clonal disorder in which sustained megakaryocyte proliferation leads to an increase in the number of circulating platelets. It is silent disorder and is diagnosed as high platelet counts with or without associated symptoms or as an accidental finding. We, hereby, report a case of ET as an incidental finding during screening of a potential platelet donor. Donors with high platelet count should be investigated properly to rule out ET. The role of transfusion medicine specialist is not only to recruit donors but also to identify such donors during screening and counsel them for detailed investigation and proper management. Wolters Kluwer - Medknow 2020 2020-07-24 /pmc/articles/PMC7607989/ /pubmed/33162716 http://dx.doi.org/10.4103/ajts.AJTS_114_19 Text en Copyright: © 2020 Asian Journal of Transfusion Science http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms. |
spellingShingle | Case Report Navkudkar, Anisha Desai, Priti Rajadhyaksha, Sunil Unexpected high platelet counts in a potential platelet donor: A clue to essential thrombocythemia |
title | Unexpected high platelet counts in a potential platelet donor: A clue to essential thrombocythemia |
title_full | Unexpected high platelet counts in a potential platelet donor: A clue to essential thrombocythemia |
title_fullStr | Unexpected high platelet counts in a potential platelet donor: A clue to essential thrombocythemia |
title_full_unstemmed | Unexpected high platelet counts in a potential platelet donor: A clue to essential thrombocythemia |
title_short | Unexpected high platelet counts in a potential platelet donor: A clue to essential thrombocythemia |
title_sort | unexpected high platelet counts in a potential platelet donor: a clue to essential thrombocythemia |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7607989/ https://www.ncbi.nlm.nih.gov/pubmed/33162716 http://dx.doi.org/10.4103/ajts.AJTS_114_19 |
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