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Interleukin-6 receptor blockade with subcutaneous tocilizumab improves coagulation activity in patients with COVID-19
BACKGROUND: Many COVID-19 patients develop a hyperinflammatory response which activates blood coagulation and may contribute to the occurrence of thromboembolic complications. Blockade of interleukin-6, a key cytokine in COVID-19 pathogenesis, may improve the hypercoagulable state induced by inflamm...
Autores principales: | Di Nisio, Marcello, Potere, Nicola, Candeloro, Matteo, Spacone, Antonella, Pieramati, Leonardo, Ferrandu, Giovanna, Rizzo, Giulia, La Vella, Matteo, Di Carlo, Silvio, Cibelli, Donatella, Parruti, Giustino, Levi, Marcel, Porreca, Ettore |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
European Federation of Internal Medicine. Published by Elsevier B.V.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7608031/ https://www.ncbi.nlm.nih.gov/pubmed/33162299 http://dx.doi.org/10.1016/j.ejim.2020.10.020 |
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